



The coronavirus pandemic led to shortages in the blood supply across the U.S. Scientists around the world are working on a potential solution. The Future of Everything looks at the process of making artificial blood.
Illustration: Timothy Wong

Nature reviews: Engineering yeast to produce medicines, immunity to Covid-19, and the mechanism of anaesthetic action.
In this episode:
00:44 Making medicine with yeast
The tropane alkaloids are an important class of medicine, but they are produced agriculturally leaving them vulnerable to extreme weather and world events. Now, researchers have engineered yeast to produce these important molecules. Research Article: Srinivasan and Smolke
06:36 Coronapod
We discuss the complex story of immunity to COVID-19, and how this may affect vaccine development. News Feature: What the immune response to the coronavirus says about the prospects for a vaccine
16:33 Research Highlights
The neurological reason for overindulgence, and the bacteria that harness copper electrodes. Research Highlight: The brain circuit that encourages eating for pleasure; Research Highlight: Microbes with mettle build their own electrical ‘wires’
19:07 The molecular mechanisms of general anaesthetics
Despite over a century of use, there’s a lot we don’t know about how anaesthetics function. This week, researchers have identified how some of them they bind to a specific neuronal receptor. Research Article: Kim et al.
26:34 Briefing Chat
Whilst the Nature Briefing is on its summer holidays, we take a look at some other science from around the web. This time we discuss Elon Musk’s latest showcase of a brain-chip, and the physics behind how boats can float upside down on levitating liquid. New Scientist: Elon Musk demonstrated a Neuralink brain implant in a live pig; Business Insider: Elon Musk’s AI brain chip company Neuralink is doing its first live tech demo on Friday. Here’s what we know so far about the wild science behind it.; Research Article: Apffel et al.; Video: The weird physics of upside down buoyancy
Global satellite data indicate wildfires are becoming bigger and more intense. WSJ talks with NASA’s Doug Morton to understand the science behind what’s making the planet more flammable and making fires harder to control.
Noah Berger/Associated Press

Staff Writer Paul Voosen talks with host Sarah Crespi about how Arctic sea ice is under attack from above and below—not only from warming air, but also dangerous hot blobs of ocean water.
Next, Damien Fordham, a professor and global change ecologist at the University of Adelaide, talks about how new tools for digging into the past are helping catalog what happened to biodiversity and ecosystems during different climate change scenarios in the past. These findings can help predict the fate of modern ecosystems under today’s human-induced climate change. And in our books segment, Kiki Sanford talks with author Carl Bergstrom about his new book: Calling Bullshit: The Art of Skepticism in a Data-Driven World.

August 26, 2020: Protecting delicate quantum bits from radiation, convalescent plasma for serious Covid-19 patients and a competition to replicate findings from ancient computer code.
In this episode:
01:04 Quantum computers vs ionizing radiation
The quantum bits, or ‘qubits’, central to the operation of quantum computers are notoriously sensitive. Now, researchers have assessed the damaging effects that ionizing radiation can have on these qubits and what can be done about it. Research Article: Vepsäläinen et al.
08:15 Coronapod
We discuss the US Food and Drug Administration’s decision to authorize convalescent plasma for emergency use in COVID-19 patients. As accusations of political interference fly, what might this mean for the future of the US coronavirus response?
20:39 Research Highlights
Finding new populations of a long-lost elephant shrew, and the hunting method of ancient ichthyosaurs. Research Highlight: An elephant-nosed creature ‘lost to science’ was living just next door; Research Highlight: An extinct reptile’s last meal shows it was a grip-and-tear killer
22:34 The reproducibility of computer code
Many scientists have published papers based on code. Recently though, a gauntlet was thrown down for researchers to try to replicate their code, 10 years or more after they wrote it. Tech Feature: Challenge to scientists: does your ten-year-old code still run?
28:06 Briefing Chat
We take a look at some highlights from the Nature Briefing. This time we discuss a cancer diagnosis in a dinosaur, and how to brew yourself a career outside of academia. Science: Doctors diagnose advanced cancer—in a dinosaur; Nature Careers Feature: The brews and bakes that forged career paths outside academia



In this Nature podcast: a new way to produce aerogels opens up their use, the countries that collect Covid-19 data effectively, and understanding how sulfur can change state between two liquids.
In this episode:
01:05 Printing aerogels
Aerogels are materials with impressive insulating properties, but they’re difficult to handle, due to their innate fragility. Now, researchers have shown a new way to 3D print the most common form of aerogel, opening up a range of potential new applications. Research Article: Zhao et al.
07:00 Coronapod
To provide targeted public health interventions during the pandemic, it’s vital that data are collected and shared effectively. We discuss the countries doing this well, and find out how fragmented systems are preventing epidemiologists from giving up-to-date information on outbreaks.
21:11 Research Highlights
Fats in the blood as a possible marker of autism, and the selfish component to solar panel adoption. Research Highlight: Fats in the blood linked to autism; Research Highlight: Self-interest powers decision to go solar
23:24 Liquid-liquid transitions
It’s been thought that some liquids may be able to exist in two distinct states, but evidence has been scarce. Now, researchers show that sulfur can exist in two liquid states, and have discovered some insights into how this might occur. Research Article: Henry et al.; Video: 24 hours in a synchrotron
30:09 Briefing Chat
We take a look at some highlights from the Nature Briefing. This time we discuss the English language’s dominance in science, and how to make squid transparent. Symmetry: Physics in a second language; OneZero: The First Gene-Edited Squid in History Is a Biological Breakthrough