From a Science Magazine online article:
Antibiotic use diminished the gut microbiome composition and impaired the ability of the immune system to generate antibodies. Treatment with antibiotics also disturbed bile acid metabolism and caused inflammatory responses.
From the original findings the Journal “Cell.com”:
Emerging evidence indicates a central role for the microbiome in immunity. However, causal evidence in humans is sparse. Here, we administered broad-spectrum antibiotics to healthy adults prior and subsequent to seasonal influenza vaccination. Despite a 10,000-fold reduction in gut bacterial load and long-lasting diminution in bacterial diversity, antibody responses were not significantly affected. However, in a second trial of subjects with low pre-existing antibody titers, there was significant impairment in H1N1-specific neutralization and binding IgG1 and IgA responses.
In addition, in both studies antibiotics treatment resulted in (1) enhanced inflammatory signatures (including AP-1/NR4A expression), observed previously in the elderly, and increased dendritic cell activation; (2) divergent metabolic trajectories, with a 1,000-fold reduction in serum secondary bile acids, which was highly correlated with AP-1/NR4A signaling and inflammasome activation. Multi-omics integration revealed significant associations between bacterial species and metabolic phenotypes, highlighting a key role for the microbiome in modulating human immunity.
In summary, dietary fructose, but not glucose, supplementation of HFD impairs mitochondrial size, function, and protein acetylation, resulting in decreased fatty acid oxidation and development of metabolic dysregulation.
Kaia’s iOS and Android apps were developed with the help of physiotherapists, pain management physicians, orthopedic surgeons, and clinical psychologists, the company claims, and are registered as Class 1 medical devices with the Food and Drug Administration. They serve up video clips covering basic back and COPD pain information and step-by-step physiotherapy exercises, in addition to psychological strategies, such as mindfulness and muscle relaxation.
“As a result, today’s epidemic of physical inactivity in conjunction with highly processed, high-sodium diets contributes to thicker, stiffer hearts that compromise the heart’s ability to cope with endurance physical activity, and importantly this may start to occur prior to increases in resting blood pressure,” explains Shave.
…a new 
There may be no easy fix for the loneliness epidemic plaguing the nation, but helping people cope with hearing loss could be one key to tackling this complex problem. Hearing loss affects 1 of every 5 people and is strongly linked to loneliness: Every decibel drop in perception in people under 70 increases the odds of becoming severely lonely by 7%, 
Our findings suggest that higher adherence to a Mediterranean diet is associated with better cognitive performance, and therefore less cognitive decline, in older but not middle-aged individuals.
“We are extremely proud of what we have accomplished, from the ability to 3D bioprint human cardiac tissue last summer to a mini heart with full structure now. These milestones are a testament to the hard work of our team and the proprietary process we have developed that enables this type of scientific achievement,” said Birla in a press release. “We believe we are at the forefront of whole heart bioengineering, a field that has matured quickly over the last year, and well-positioned to continue our rapid scientific advancement.”
Researchers say they’ve successfully plunged human livers to subzero temperatures and then warmed them back up.
Boomers Daily 