UCSF orthopedic surgeon Dr. Paul Toogood discusses the types and origins or Arthritis.
Tag Archives: Arthritis
Health: “Living With Arthritis” (Mayo Clinic)
On the Mayo Clinic Radio program, Dr. John M. Davis III, a Mayo Clinic rheumatologist, discusses arthritis, and the latest edition of the book, “Mayo Clinic on Arthritis — How to Manage Pain and Lead an Active Life”.
If you have arthritis, you are not alone. More than 50 million Americans suffer from arthritis and it is the No. 1 cause of disability in the country. Arthritis is the swelling and tenderness of one or more of your joints, causing joint pain and stiffness that typically worsen with age. Of the over 100 kinds of arthritis, the two most common are osteoarthritis and rheumatoid arthritis. Learn more about arthritis: https://www.mayoclinic.org/diseases-c…
Research: Scientists Find Protein To Regulate Immune Attacks, Reduce Rheumatoid Arthritis
From a New Atlas online article:
Scientists have just discovered a new mechanism that can be key in regulating these immune attacks, raising new hopes of drugs that can protect against joint inflammation and the ailments it can bring.
Through the use of the CRISPR gene-editing tool, the Karolinska Institutet scientists have now shed further light on the role they play in inflammation. The technology enabled the team to make adjustments to a set of hand-picked immune cell genes as a way of learning how those tweaks can impact the behavior of the cells.
“The results we obtained using CRISPR were key to quickly understanding how the system under study is regulated,” says Dr Wermeling. “I have high hopes that the experimental use of CRISPR will be hugely important to our understanding of how immune-cell behavior is regulated, and that this can guide us in the development of new efficacious drugs.”
Health Studies: NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) Increase Heart Failure Risk For Arthritis Patients
From a Harvard Medical School release:
Researchers matched 7,743 people with osteoarthritis with 23,229 healthy people who rarely or never took NSAIDs. People with osteoarthritis had a 42% higher risk of heart failure and a 17% higher risk of coronary artery disease compared with healthy people. After controlling for a range of factors that contribute to heart disease (including high body mass index, high blood pressure, and diabetes), they concluded that 41% of the increased risk of heart disease related to osteoarthritis was due to the use of NSAIDs.
To manage the painful joint disease known as osteoarthritis, people often take ibuprofen (Advil, Motrin) and naproxen (Aleve, Anaprox). But these and related drugs — known as NSAIDs — may account for the higher rates of heart disease seen in people with osteoarthritis, a new study suggests.
To read more: https://www.health.harvard.edu/heart-health/pain-relievers-a-cause-of-higher-heart-risk-among-people-with-arthritis
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