Tag Archives: Urine Tests

Digital Medicine: Apps For Smartphones, Machine Learning To Treat Kidney Disease (The Lancet)

From a The Lancet online article (January 18, 2020):

The Lancet logoSmartphone app-based platforms for urine testing could improve adherence to albumin creatinine ratio (ACR) testing. One study showed screening of at-risk patients almost doubled with a home urine test kit that uses a smartphone camera to easily and accurately quantify ACR from a user-performed urine dipstick. If independently validated in a large, diverse population, this low-cost strategy could change the often dim trajectory for individuals with declining kidney function. Chronic Kidney Disease A Global Crisis Siemens Healthineers

In the outpatient setting, a Japanese team used machine learning and natural language processing to predict disease progression and need for dialysis over 6 months in patients with diabetic nephropathy. And while the increased risk of contrast-induced acute kidney injury has been long appreciated, a machine learning algorithm trained and tested on 3 million adults effectively quantified the degree of kidney injury on the basis of the volume of contrast used and individual patient-level characteristics.

Read full article (PDF)

Top Science Podcasts: A New Antibiotic From Nematodes, “Grants” Thru Lotteries (Nature)

Nature PodcastBenjamin Thompson brings you the latest science news. This week, an antibiotic that targets difficult to treat bacteria, and a roundup of the latest science news.

In this episode:

00:49 Discovering darobactin

Researchers looked inside nematode guts and have identified a new antibiotic with some useful properties. Research Article: Imai et al.

05:45 Research Highlights

Using urine as a health metric, and sniffing out book decay with an electronic nose. Research Article: Miller et al.Research Article: Veríssimo et al.

07:54 News Chat

Adding an element of chance to grant funding, a continental butterfly-sequencing project, and tracking endangered animals via traces of their DNA. News: Science funders gamble on grant lotteriesNews: Every butterfly in the United States and Canada now has a genome sequenceNews: Rare bird’s detection highlights promise of ‘environmental DNA’

To read more: https://www.nature.com/articles/d41586-019-03588-z

Health: Asymptomatic Bacteriuria Diagnosis In Older Patients Should Not Require Antibiotics

From a New York Times online article:

Asymtomatic Bacteriuria DefinitionAt Dr. Soong’s hospital, withholding the results of urine cultures, unless doctors actually called the microbiology lab to request them, reduced prescriptions for asymptomatic bacteriuria to 12 percent from 48 percent of non-catheterized patients, with no loss of safety.

“The extra step of having the clinician call eliminated a lot of frivolous testing,” Dr. Soong said.

In patients who have none of the typical symptoms of a urinary tract infection — no painful or frequent urination, no blood in the urine, no fever or lower abdominal tenderness — lab results detecting bacteria in the urine don’t indicate infection and thus shouldn’t trigger treatment.

Older people, and nursing home residents in particular, often have urinary systems colonized by bacteria; they will have a positive urine test almost every time, but they’re not sick.

To read more: https://www.nytimes.com/2019/10/14/health/urine-tests-elderly.html