Tag Archives: mRNA Vaccines

Covid-19: Penn Medicine Explains mRNA Vaccines

Vaccines are about to change the world…again. mRNA Vaccines are currently being used to battle COVID-19, and have the potential to eradicate diseases like HIV, herpes, sickle cell anemia, and even cancer. Learn how the vaccines work and where the technology could be headed in this explainer video.

Currently, the Pfizer-BioNTech and Moderna vaccines for COVID-19 use the mRNA technology developed at Penn by infectious disease expert Drew Weissman, MD, PhD, along with longtime research collaborator Katalin Karikó, PhD, an adjunct associate professor. Dr. Weissman has been studying mRNA vaccines for decades. This technology could change the way future vaccines are made to prevent countless other diseases.

Covid-19: ‘How Do The Leading Vaccines Work?’

As countries like the United States and United Kingdom inoculate their residents with never-before used vaccine technology, others, including Russia, China, and India, are investing in more traditional approaches, like inactivated coronavirus vaccines. But no matter the technique, together they have the potential to create multiple lines of defense against SARS-CoV-2. Science senior correspondent Jon Cohen explains how each of these vaccines can protect us from severe illness—and what understanding the details of our immune responses could mean for the future of human trials.

Covid-19: ‘The Rise Of The RNA Vaccines’ (Podcast)

Benjamin Thompson, Noah Baker and Elie Dolgin discuss RNA vaccines.

In this episode:

01:16 How RNA vaccines came to prominence

In less than a year, two RNA vaccines against COVID-19 were designed, tested and rolled out across the world. We discuss these vaccines’ pros and cons, how RNA technology lends itself to rapid vaccine development, and what this means for the fight against other diseases.

News feature: How COVID unlocked the power of RNA vaccines

09:20 The hurdles for trialling new COVID-19 vaccines

Multiple candidates for new COVID-19 vaccines are still being developed, which may offer advantages over the vaccines currently available. However, running placebo-controlled trials of these candidates is becoming increasingly difficult, so researchers are looking for different ways to evaluate them.

News: Search for better COVID vaccines confounded by existing rollouts

14:45 How long will COVID vaccines be effective?

There is much concern around the world about two faster-spreading variants of SARS-CoV-2. We get an update on whether these variants could render vaccines ineffective.

News: Could new COVID variants undermine vaccines? Labs scramble to find out

Covid-19: ‘How mRNA Vaccines Work’ (Video)

Messenger RNA—or mRNA—vaccines have been in development for decades, and are now approved for use against COVID-19. Here’s how they work and what you should know about them. Visit https://www.jhsph.edu/covid-19​ for even more resources.