Tag Archives: Visceral Fat

Health Research: Type 2 Diabetes Caused By “Overflow Of Fat” From Liver To Pancreas

December 26, 2019 She Seeks Serene Leave a comment

From a Newcastle University news release:

“When fat cannot be safely stored under the skin, it is then stored inside the liver, and over-spills to the rest of the body including the pancreas. This ‘clogs up’ the pancreas, switching off the genes which direct how insulin should effectively be produced, and this causes Type 2 diabetes.”

This latest paper builds on previous Newcastle studies supported by Diabetes UK showing exactly why Type 2 diabetes can be reversed back to normal glucose control. Those studies led to the large DiRECT trial which showed that Primary Care staff can achieve remission of Type 2 diabetes by using a low calorie diet with support to maintain the weight loss.

A quarter of participants achieved a staggering 15 kg or more weight loss, and of these, almost nine out of 10 people put their Type 2 diabetes into remission. After two years, more than one third of the group had been free of diabetes and off all diabetes medication for at least two years.

In 2020, this approach to management of short duration Type 2 diabetes is to be piloted in the NHS in up to 5,000 people across England, and a similar programme is being rolled out in Scotland.

Diet, Health, Studies

Diet Studies: “10-Hour Time -Restricted Eating” (TRE) Lowers Weight, Visceral Fat & Blood Pressure

December 6, 2019 She Seeks Serene Leave a comment

From a Cell Metabolism online study release:

Ten-hour time-restricted eating (TRE) limits daily dietary intake to a consistent 10-h window, creating a 14-h nightly fast. Researchers studied whether TRE for 12 weeks in people with metabolic syndrome receiving standard medical care (including medications to lower cholesterol and blood pressure) improves markers of health. TRE led to weight loss, healthier body composition (including decreased waist circumference), lower blood pressure and levels of cardiovascular disease-promoting lipids (i.e., “bad cholesterol” levels), and more restful sleep. TRE could be an effective dietary intervention to help those with metabolic syndrome.

Time-restricted eating (TRE) is an emerging dietary intervention that aims to maintain a consistent daily cycle of feeding and fasting to support robust circadian rhythms (Panda, 2016). Circadian regulation of the endocrine system, autonomic nervous system, and nutrient metabolism contributes to metabolic and physiological homeostasis (Asher and Sassone-Corsi, 2015,Panda, 2016). Both erratic eating patterns and eating over an extended period of time during the 24-h day can disrupt circadian rhythms.

To read entire study: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30611-4

Health, Studies

Obesity Studies: Visceral (Abdominal) Fat Is Major Risk Factor For Type 2 Diabetes, Atherosclerosis & Cardiovascular Disease

August 21, 2019 She Seeks Serene Leave a comment

From The Lancet Diabetes & Endocrinology:

This joint position statement from the International Atherosclerosis Society and the International Chair on Cardiometabolic Risk Working Group on Visceral Obesity summarises the evidence for visceral adiposity and ectopic fat as emerging risk factors for type 2 diabetes, atherosclerosis, and cardiovascular disease, with a focus on practical recommendations for health professionals and future directions for research and clinical practice.

Findings from epidemiological studies over the past 30 years have shown that visceral adipose tissue, accurately measured by CT or MRI, is an independent risk marker of cardiovascular and metabolic morbidity and mortality. Emerging evidence also suggests that ectopic fat deposition, including hepatic and epicardial fat, might contribute to increased atherosclerosis and cardiometabolic risk. We discuss the measurement of visceral and ectopic fat, pathophysiology and contribution to adverse health outcomes, response to treatment, and lessons from a public health programme targeting visceral and ectopic fat. We identify knowledge gaps and note the need to develop simple, clinically applicable tools to be able to monitor changes in visceral and ectopic fat over time. Finally, we recognise the need for public health messaging to focus on visceral and ectopic fat in addition to excess bodyweight to better combat the growing epidemic of obesity worldwide.