Microbiome expands the genetic and functional capacity of its human host. Susan Lynch explains that human microbiome develops early in life and that gut microbes shape immune function and relate to disease outcomes in childhood.

She also explores next-generation microbiome therapeutics and research.
Dr. Grace Dammann, medical director of the Pain Clinic at Laguna Honda Hospital, and seven of her colleagues talk about what does and does not work in the treatment of chronic pain. She talks as both a patient and a provider. There is also a discussion of various non-pharmacologic and complementary medicine modalities to treat pain.
Orthopedic surgeon Dr. Daniel Thuillier looks at the options to treat severe ankle pain from nonsteroidal anti-inflammatory drugs to surgery including ankle replacement and ankle fusion.