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Before its computer crashed, venerable NASA probe may have entered mysterious new region beyond the Solar System
Mouse study contradicts landmark finding, but some question its methodology
Pathogen that kills victims within days leaps from Caribbean to Red Sea
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A cell-by-cell look at neuropsychiatric diseases
DNA sequences are connected to genes and functions in the developing and adult brain
DNA study implicates medieval warfare and colonial trade
Scientific American (May 15, 2024): The June 2024 issue features:
BENJAMIN CASSIDY
RACHEL NUWER
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In AU$940 million deal, PsiQuantum will build “utility scale” facility
Draft evaluation calls 2016 decision to change oral vaccines a “failure”
Novel effort comes as study finds key receptor for avian flu virus in udders, where the virus flourishes
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Claudia Sheinbaum Pardo would be first researcher to lead the country, but critics worry she’ll be as hostile to science as her predecessor
Scientists test bighorn sheep, bears, moose, rats, and dozens of other species to track how SARS-CoV-2 moves between humans and wildlife
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Vitamin D modulates intestinal epithelial cell function to enhance antitumor microbes
The gut microbiome has been shown to modulate the response of cancer patients to therapy, but precisely how microbiota affect anticancer immunity is still being elucidated. Giampazolias et al. report that vitamin D bioavailability in mice influences the composition of the gut microbiome (see the Perspective by Franco and McCoy). After dietary manipulation, vitamin D levels were observed to affect gut bacteria, which in turn improved cancer immunotherapy and antitumor immunity. In humans, low vitamin D levels were correlated with tumor development, and gene signatures of vitamin D activity were associated with improved patient responses to immunotherapy. These findings highlight the connection between vitamin D and the immune system through gut bacteria and may have applications for improving cancer therapies.
Lake Tanganyika contains one of the most impressive adaptive radiations, with about 250 species of cichlid occupying a variety of niches. Much research has focused on understanding the drivers of this and other adaptive radiations. Trembo et al. looked in depth at 57 of these cichlid species with regard to their behavior, ecomorphology, and genomics. They found that one behavior in particular, a tendency to explore, was related to niche adaptation, and they identified a regulatory gene that is highly associated with this behavior. These findings suggest the existence of an adaptive syndrome driven in part by a tendency to explore what is new.
NASA’s JWST telescope traces burst to a supernova but finds a puzzling lack of heavy elements
Exposing monitor lizards to thousands of young cane toads helped them survive once the adult toads invaded
Suit seeks to overturn state law targeting graduate and postdocs from China and other “countries of concern”
Meteorites suggest tumult occurred around the time of the Moon’s formation
Ancient prophecies of worlds destroyed by fire are becoming realities. How will we respond?
New discoveries demystify the bizarre force that binds atomic nuclei together
HARVARD MAGAZINE May/June2024 :
How long will the world’s forests impound carbon below ground?
by Jonathan Shaw
MARYVILLE, Tennessee, lies near the foothills of the Great Smoky Mountains, a range home to more tree species than exist in all of Europe. Benton Taylor grew up amidst this abundance, but as a boy, he barely noticed the plants. In the nearby national park, a family friend was raising—together with a menagerie of other mammals—a pair of bears orphaned as cubs. Taylor dreamed of studying these apex denizens of the forest, who forage at the top of the food chain. But as his education and understanding grew, his curiosity shifted to seed-dispersing animals, plants, and the soil and nutrients that sustain them: a trip down the trophic pyramid, driven by an appreciation of forests as ecological systems in which plants are primary producers. “Now I’ve half moved into the basement,” jokes the assistant professor of organismic and evolutionary biology, whose research encompasses the strategies plants use to obtain essential nutrients such as nitrogen, and how that, in turn, affects their ability to store another vital element with a global climate impact: carbon.
by Nina Pasquini
DIVERSIFYING one’s assets is useful not only in finance but also in diet, according to an October study from the Harvard T.H. Chan School of Public Health (HSPH). Though not many people have heard of the “portfolio diet”—consisting of plant-based foods proven to lower unhealthy cholesterol, such as nuts, oats, berries, and avocados—it is one of the easiest ways to improve long-term cardiovascular health. “The idea was that each of these foods lowers cholesterol quite minimally, but if you make a whole diet based on these different foods, you will see large reductions in [unhealthy] cholesterol,” said Andrea Glenn, an HSPH postdoctoral research fellow in nutrition and the lead author of the study. The more of these foods one eats, the higher the protection—but one need not include them all to reap the diet’s benefits, she said. “Like a business portfolio, you can choose the ones you want.”
Mina Cikara explores how political tribalism feeds the American bipartisan divide.
by Max J. Krupnick
Was Lucy the mother of us all? Fifty years after her discovery, the 3.2-million-year-old skeleton has rivals
Flexible fiber electronics couple with the human body for wireless tactile sensing
Boomers Daily 