Tag Archives: Circadian Rhythms

Studies: Disrupted Sleep Cycles & Dopamine Linked; Craving “High-Calorie Food” & Obesity Are Result

From a NeuroscienceNews.com online release article (01/02/20):

During the years 1976 through 1980, 15% of U.S. adults were obese. Today, about 40%of adults are obese. Another 33% are overweight.

“But, of course, food is now abundant, and our next meal is as close as the kitchen, or the nearest fast-food drive-through, or right here on our desk. Often, these foods are high in fats, sugars, and therefore calories, and that’s why they taste good. It’s easy to overconsume, and, over time, this takes a toll on our health.”

Current Biology Journal Dopamine Signaling and Weight Gain January 2 2020
Dopamine Signaling in the Suprachiasmatic Nucleus Enables Weight Gain Associated with Hedonic Feeding – Current Biology January 2, 2020

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In a study published Thursday in the journal Current Biology, Güler and his colleagues demonstrate that the pleasure center of the brain that produces the chemical dopamine, and the brain’s separate biological clock that regulates daily physiological rhythms, are linked, and that high-calorie foods – which bring pleasure – disrupt normal feeding schedules, resulting in overconsumption. Using mice as study models, the researchers mimicked the 24/7 availability of a high-fat diet, and showed that anytime snacking eventually results in obesity and related health problems.

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Sleep Studies: Increase In Preventable Diseases Tied To Disrupted “Circadian Rhythms” (Harvard)

From a Sleep Review Magazine online article:

Nighttime EatingWhen people are awake during the night, their behaviors are often mismatched with their internal body clocks. This can lead to nighttime eating, which can influence the way the body processes sugar and could lead to a higher risk in diabetes. “What happens when food is eaten when you normally should be fasting?” Scheer asked the audience. “What happens is that your glucose tolerance goes out the window….So your glucose levels after a meal are much higher.” This can increase people’s risk for diabetes.

Frank Scheer, PhD, professor of medicine at Harvard Medical School and director of the medical chronobiology program at Brigham and Women’s Hospital in Boston, says disruption of the body’s circadian rhythms may be one major reason why more Americans are living with preventable diseases. During his keynote talk at the 2019 AAST annual meeting in St. Louis, he outlined how recent research supports the hypothesis that higher rates of shiftwork and other forms of nighttime disruption could be contributing to increased rates of obesity, diabetes, and other common ailments.

To read more: http://www.sleepreviewmag.com/2019/10/circadian-rhythm-disruption-increase-preventable-diseases/