Microfluidics | Boomers Daily

Nature looks at: Keeping electronics from overheating, Covid-19 changes, and how to include minority populations in genetic analyses.

In this episode:

00:46 Cool computers

Keeping components cool is a major hurdle when it comes to increasing electronic power. This week, we find out about a new way to integrate tiny microfluidic channels directly into circuits, to help keep them cool. Research Article: van Erp et al.

06:57 Coronapod

By comparing coronavirus genomes taken from people around the world, researchers are getting an idea of how SARS-CoV-2 is changing as it spreads. We discuss a particular genetic mutation that rapidly became dominant early in the pandemic, and the effect it may have had on the outbreak. News: The coronavirus is mutating — does it matter?

21:41 Research Highlights

How rock avalanches can cause destructive air blasts, and melting glaciers cause lakes to grow. Research Highlight: The violent blasts that can add to an avalanche’s devastation; Research Article: Shugar et al.

23:59 The people left out of genetic studies

Minority populations are often underrepresented in genetic study recruitment. However, even when data about them is collected it may go unused. We find out why, and what can be done about it. Comment: Don’t ignore genetic data from minority populations

30:51 Briefing Chat

We discuss some of the latest stories highlighted in the Nature Briefing. This week we discuss how bacterially-infected mosquitoes could curb dengue fever, and some surprisingly large black holes. Nature News: The mosquito strategy that could eliminate dengue; Nature News: ‘It’s mindboggling!’: astronomers detect most powerful black-hole collision yet

From a Caltech online news release:

“Such wearable sweat sensors have the potential to rapidly, continuously, and noninvasively capture changes in health at molecular levels,” Gao says. “They could enable personalized monitoring, early diagnosis, and timely intervention.”

The development of such sensors would allow doctors to continuously monitor the condition of patients with illnesses like cardiovascular disease, diabetes, or kidney disease, all of which result in abnormal levels of nutrients or metabolites in the bloodstream. Patients would benefit from having their physician better informed of their condition, while also avoiding invasive and painful encounters with hypodermic needles.

Gao’s work is focused on developing devices based on microfluidics, a name for technologies that manipulate tiny amounts of liquids, usually through channels less than a quarter of a millimeter in width. Microfluidics are ideal for an application of this sort because they minimize the influence of sweat evaporation and skin contamination on the sensing accuracy. As freshly supplied sweat flows through the microchannels, the device can make more accurate measurements of sweat and can capture temporal changes in concentrations.