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Despite failing hardware, NASA has no plans to pursue a servicing mission to the aging, iconic instrument
New studies include health data collected from space tourists on first privately funded orbital mission
Ancient DNA shows continuity between living and ancient Maya communities
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Deforestation and climate change may be helping Oropouche virus spread far beyond the Amazon Basin
Achievement demonstrates feasibility of making all of life’s code easily searchable, researchers say
Comparative genomics elucidates the steps enabling heat production in fat tissue
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Before its computer crashed, venerable NASA probe may have entered mysterious new region beyond the Solar System
Mouse study contradicts landmark finding, but some question its methodology
Pathogen that kills victims within days leaps from Caribbean to Red Sea
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A cell-by-cell look at neuropsychiatric diseases
DNA sequences are connected to genes and functions in the developing and adult brain
DNA study implicates medieval warfare and colonial trade
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In AU$940 million deal, PsiQuantum will build “utility scale” facility
Draft evaluation calls 2016 decision to change oral vaccines a “failure”
Novel effort comes as study finds key receptor for avian flu virus in udders, where the virus flourishes
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Claudia Sheinbaum Pardo would be first researcher to lead the country, but critics worry she’ll be as hostile to science as her predecessor
Scientists test bighorn sheep, bears, moose, rats, and dozens of other species to track how SARS-CoV-2 moves between humans and wildlife
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Vitamin D modulates intestinal epithelial cell function to enhance antitumor microbes
The gut microbiome has been shown to modulate the response of cancer patients to therapy, but precisely how microbiota affect anticancer immunity is still being elucidated. Giampazolias et al. report that vitamin D bioavailability in mice influences the composition of the gut microbiome (see the Perspective by Franco and McCoy). After dietary manipulation, vitamin D levels were observed to affect gut bacteria, which in turn improved cancer immunotherapy and antitumor immunity. In humans, low vitamin D levels were correlated with tumor development, and gene signatures of vitamin D activity were associated with improved patient responses to immunotherapy. These findings highlight the connection between vitamin D and the immune system through gut bacteria and may have applications for improving cancer therapies.
Lake Tanganyika contains one of the most impressive adaptive radiations, with about 250 species of cichlid occupying a variety of niches. Much research has focused on understanding the drivers of this and other adaptive radiations. Trembo et al. looked in depth at 57 of these cichlid species with regard to their behavior, ecomorphology, and genomics. They found that one behavior in particular, a tendency to explore, was related to niche adaptation, and they identified a regulatory gene that is highly associated with this behavior. These findings suggest the existence of an adaptive syndrome driven in part by a tendency to explore what is new.
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