First up this week, Senior Correspondent Daniel Clery talks with host Sarah Crespi about how Breakthrough Listen—a privately funded initiative that aims to spend $100 million over 10 years to find extraterrestrial intelligent life—has changed the hunt for alien intelligence.
And as part of a special issue on the Genotype-Tissue Expression (GTEx) project, Brandon Pierce, a professor in the Departments of Public Health Sciences and Human Genetics at the University of Chicago, joins Sarah to discuss his group’s work on variation in the protective caps at the end of our chromosomes. The gradual shortening of these caps, also known as telomeres, has been associated with aging. Read more from the GTEx special issue.
Nature reviews: Engineering yeast to produce medicines, immunity to Covid-19, and the mechanism of anaesthetic action.
In this episode:
00:44 Making medicine with yeast
The tropane alkaloids are an important class of medicine, but they are produced agriculturally leaving them vulnerable to extreme weather and world events. Now, researchers have engineered yeast to produce these important molecules. Research Article: Srinivasan and Smolke
19:07 The molecular mechanisms of general anaesthetics
Despite over a century of use, there’s a lot we don’t know about how anaesthetics function. This week, researchers have identified how some of them they bind to a specific neuronal receptor. Research Article: Kim et al.
Staff Writer Paul Voosen talks with host Sarah Crespi about how Arctic sea ice is under attack from above and below—not only from warming air, but also dangerous hot blobs of ocean water.
Next, Damien Fordham, a professor and global change ecologist at the University of Adelaide, talks about how new tools for digging into the past are helping catalog what happened to biodiversity and ecosystems during different climate change scenarios in the past. These findings can help predict the fate of modern ecosystems under today’s human-induced climate change. And in our books segment, Kiki Sanford talks with author Carl Bergstrom about his new book: Calling Bullshit: The Art of Skepticism in a Data-Driven World.
August 26, 2020: Protecting delicate quantum bits from radiation, convalescent plasma for serious Covid-19 patients and a competition to replicate findings from ancient computer code.
In this episode:
01:04 Quantum computers vs ionizing radiation
The quantum bits, or ‘qubits’, central to the operation of quantum computers are notoriously sensitive. Now, researchers have assessed the damaging effects that ionizing radiation can have on these qubits and what can be done about it. Research Article: Vepsäläinen et al.
08:15 Coronapod
We discuss the US Food and Drug Administration’s decision to authorize convalescent plasma for emergency use in COVID-19 patients. As accusations of political interference fly, what might this mean for the future of the US coronavirus response?
Many scientists have published papers based on code. Recently though, a gauntlet was thrown down for researchers to try to replicate their code, 10 years or more after they wrote it. Tech Feature: Challenge to scientists: does your ten-year-old code still run?
In this Nature podcast: a new way to produce aerogels opens up their use, the countries that collect Covid-19 data effectively, and understanding how sulfur can change state between two liquids.
In this episode:
01:05 Printing aerogels
Aerogels are materials with impressive insulating properties, but they’re difficult to handle, due to their innate fragility. Now, researchers have shown a new way to 3D print the most common form of aerogel, opening up a range of potential new applications. Research Article: Zhao et al.
07:00 Coronapod
To provide targeted public health interventions during the pandemic, it’s vital that data are collected and shared effectively. We discuss the countries doing this well, and find out how fragmented systems are preventing epidemiologists from giving up-to-date information on outbreaks.
It’s been thought that some liquids may be able to exist in two distinct states, but evidence has been scarce. Now, researchers show that sulfur can exist in two liquid states, and have discovered some insights into how this might occur. Research Article: Henry et al.; Video: 24 hours in a synchrotron
Staff Writer Robert Service talks with host Sarah Crespi about a different approach to COVID-19 testing that might be useful in response to the high numbers of cases in the United States. To break chains of transmission and community spread, the new strategy would replace highly accurate but slow polymerase chain reaction (PCR) tests with cheaper, faster tests that are less accurate but can be administered frequently.
Such tests cost between $1 and $3 compared with more than $100 for diagnostic PCR tests and give results in less than 30 minutes instead of days. Read all of our coronavirus coverage here. Also this week, Salma Mousa, a postdoctoral fellow at Stanford University, joins Sarah to talk about an experiment that added Muslim players to teams in a Christian soccer league in northern Iraq. The goal of the study was to see whether this type of social contact would change how the Christians—a threatened minority in the region—behaved toward Muslims, on and off the field.
This week’s Nature Podcast looks at: Triggering swarming behaviour in locusts, antibody therapies as a bridge to Covid-19 vaccine, and new insights into how humans synchronize.
In this episode:
01:56 Understanding swarming behaviour
Swarms of migratory locusts regularly devastate crops across the world, but why these swarms form has been a mystery. Now, a team of researchers have identified a compound that causes solitary locusts to come together in their billions – a finding that could have practical applications for preventing this behaviour. Research article: Guo et al.;News & Views: Catching plague locusts with their own scent
A satellite’s fecal find reveals that Antarctica’s emperor penguin population is much larger than previously thought, and changing how genes are named to avoid Excel’s autocorrect. Research Highlight: Satellites find penguins by following the poo; Research article: Bruford et al.
17:49 An out-of-sync arts project
A collaborative art-science project featuring a network of connected violinists has given new insights into how humans synchronize. Research article: Shahal et al.
23:51 Briefing Chat
We take a look at some highlights from the Nature Briefing. This time we find out about the odd immune system of the anglerfish, and the beetle that can pass through a frog’s digestive system without coming to harm. Wired: The Anglerfish Deleted Its Immune System to Fuse With Its Mate; Research paper: Sugiura
In 2015, after a nine-and-a-half-year journey, NASA’s New Horizons spacecraft raced past Pluto, beaming images of the dwarf planet back to Earth.
Five years after the mission, researchers are poring over images of Pluto’s far-side, which was shrouded in shadow during New Horizon’s flypast. They hope that these images will help give a better understanding of how Pluto was born and even whether a hidden ocean resides beneath the world’s icy crust.
Staff Writer Meredith Wadman joins host Sarah Crespi to discuss the risk of the novel coronavirus infection to pregnant women. Early data suggest expectant women are more likely to get severe forms of the infection and require hospitalization. Meredith describes how the biology of pregnancy—such as changes to the maternal immune system and added stress on the heart and lungs—might explain the harsher effects of the virus.
Also this week, Sarah talks with Gianluca Roscioli about his experiments with commercial razor blades and real human hair. By using a scanning electron microscope, he was able to show how something relatively soft like hair is able to damage something 50 times harder like stainless steel.
Science Editor-in-Chief Holden Thorp joins host Sarah Crespi to discuss his editorial on preventing vaccine hesitancy during the coronavirus pandemic. Even before the current crisis, fear of vaccines had become a global problem, with the World Health Organization naming it as one of the top 10 worldwide health threats in 2019. Now, it seems increasingly possible that many people will refuse to get vaccinated. What can public health officials and researchers do to get ahead of this issue?
Also this week, Sarah talks with Science Senior Correspondent Jon Cohen about his story on Chinese scientist Shi Zhengli, the bat researcher at the center of the COVID-19 origins controversy—and why she thinks President Donald Trump owes her an apology.
Finally, Geert Van der Snickt, a professor in the conservation-restoration department at the University of Antwerp, talks with Sarah about his Science Advances paper on a new process for peering into the past of paintings. His team used a combination of techniques to look beneath an overpainting on the Ghent Altarpiece by Hubert and Jan Van Eyck—a pivotal piece that showed the potential of oil paints and even included an early example of painting from an aerial view.
News, Views and Reviews For The Intellectually Curious