Tag Archives: Amyloid Beta Protein

Alzheimer’s Disease: ‘How It Starts & Progresses’

The first event in our Lab Notes online series features two researchers from our South Coast Network Centre talking about early brain changes in Alzheimer’s. Dr Karen Marshall shares her work studying how waste disposal and recycling systems in nerve cells cause damage in Alzheimer’s disease, and whether there could be ways to rescue cells from this. Dr Mariana Vargas-Caballero speaks about her research into brain cell connections and how they are affected in Alzheimer’s. The event is chaired by Dr Katy Stubbs from Alzheimer’s Research UK, and also features a Q&A session.

Boomers Health: New Blood Test Can Detect Alzheimer’s Protein Amyloid Beta 2 Decades Before Disease Onset

From a Washington University School of Medicine news release:

washu-logo2-1fxnx4qA blood test to detect the brain changes of early Alzheimer’s disease has moved one step closer to reality. Researchers from Washington University School of Medicine in St. Louis report that they can measure levels of the Alzheimer’s protein amyloid beta in the blood and use such levels to predict whether the protein has accumulated in the brain. The findings represent a key step toward a blood test to diagnose people on track to develop the devastating disease before symptoms arise.

Up to two decades before people develop the characteristic memory loss and confusion of Alzheimer’s disease, damaging clumps of protein start to build up in their brains. Now, a blood test to detect such early brain changes has moved one step closer to clinical use.

Researchers from Washington University School of Medicine in St. Louis report that they can measure levels of the Alzheimer’s protein amyloid beta in the blood and use such levels to predict whether the protein has accumulated in the brain. When blood amyloid levels are combined with two other major Alzheimer’s risk factors – age and the presence of the genetic variant APOE4 – people with early Alzheimer’s brain changes can be identified with 94% accuracy, the study found.

To read more click on following link: https://medicine.wustl.edu/news/blood-test-is-94-accurate-at-identifying-early-alzheimers-disease/